<!DOCTYPE html>
<html lang="en">

<head>
    <meta charset="UTF-8">
    <meta http-equiv="X-UA-Compatible" content="IE=edge">
    <meta name="viewport" content="width=device-width, initial-scale=1.0">
    <title>Document</title>
</head>
<style>
    * {
        margin: 0;
        padding: 0;
    }

    body {
        min-width: 600px;
    }

    #header,
    #footer {
        height: 50px;
        width: 100%;
        background: grey;
    }

    #middle,
    #left,
    #right {
        float: left;
    }

    #content {
        overflow: hidden;
    }

    #left,
    #right {
        width: 200px;
        height: 200px;
        background: pink;
    }

    #middle {
        height: 200px;
        width: 100%;
        background-color: red;
    }

    #middlea {
        background-color: violet;
        margin: 0 200px;
    }

    #left {
        margin-left: -100%;

    }

    #right {
        margin-left: -200px;
    }
</style>

<body>
    <div class="wrap">
        <div id="header">header</div>
        <div id="content">
            <div id="middle">
                <div id="middlea">middlea</div>
            </div>
            <div id="left">left</div>
            <div id="right">right</div>
        </div>
        <div id="footer">footer</div>
    </div>

</body>

</html>